People with higher levels of omega-3s in their blood may have a lower risk of dying from Covid-19 infection, a new study suggests.
The results, published in the journal Prostaglandins, Leukotrienes and Essential Fatty Acids, showed that people with a lower omega-3 index (O3I) had a relative risk of death about four times higher than those with higher values.
According to the researchers, an excessive inflammatory response known as a “cytokine storm” is a fundamental mediator of severe Covid-19 disease.
Omega-3 fatty acids (DHA and EPA) have powerful anti-inflammatory effects, and this pilot study provides evidence that these fatty acids can dampen the cytokine storm of Covid-19, the researchers said.
“While this pilot study does not meet the standard statistical significance thresholds, this pilot study – along with several lines of evidence regarding the anti-inflammatory effects of EPA and DHA – strongly suggests that these nutritionally available marine fatty acids may contribute to the risk of undesirable outcomes in Covid. to reduce -19 patients, “said lead author Arash Asher of the Samuel Oschin Comprehensive Cancer Institute at Cedars-Sinai Medical Center in the US.
For the study, the team included 100 patients who were hospitalized with Covid-19 and who had been kept for receiving blood samples.
The clinical results of these patients were obtained and the blood was analyzed for the omega-3 index (O3I, EPA + DHA levels of the red blood cell membrane) at OmegaQuant Analytics (Sioux Falls, SD). Fourteen of the patients died.
The 100 patients were divided into four quartiles based on their O3I, with 25 percent of the patients in each quartile. There was one top quartile death and 13 deaths in the remaining patients.
In age- and gender-adjusted regression analyzes, those in the top quartile were 75 percent lower at risk of death than those in the bottom three quartiles.