The latest research relating omega-3 supplements


Fish oil supplements – a particularly rich source of omega-3 fatty acids – are the most common non-vitamin / non-mineral product consumed by adults and children, according to the NIH. Almost 19 million adults and 664,000 children have taken them in the past 30 days, based on a study cited by the institute. These supplements come in a variety of forms, including fish oil, fish liver oil, krill oil, algae oil, and flaxseed oil.

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We’ve all heard the hype about the benefits of omega-3 fatty acids, but what does the research say?

Research into the health effects of omega-3 fatty acids continues, and more studies are added every year. Here is the latest evidence-based data on the subject.

Oral hygiene

Certain foods are bad for teeth and gums, including refined carbohydrates, non-vegetable proteins, and an imbalance in vitamins and minerals. On the other hand, unprocessed complex carbohydrates, vegetable proteins, omega-3 fatty acids, minerals and vitamins reduce periodontal inflammation.

According to the authors of a review published in 2021 Clinical, cosmetic and trial dentistry, “Omega-3 fatty acids have been studied extensively in recent years because they are associated with less systemic inflammation. In fact, they have shown anti-inflammatory effects that have completely overturned the historical view that the elimination of inflammation is an exclusively passive process based on the elimination of the causative factor. “

Now researchers believe that inflammation is actively resolved by “specialized pro-resolution mediators,” which are metabolites of omega-3 fatty acids – known as resolomics theory. The authors added that combining aspirin with omega-3 fatty acids further enhances the anti-inflammatory effects.

Metabolic syndrome

Treatment options for metabolic syndrome are limited. Probably the best types of intervention are early and preventive. Studies have reported a beneficial effect of omega-3 fatty acids on symptoms of metabolic syndrome.

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Results of a randomized, double-blind parallel group study 2021, published in Evidence-based complementary and alternative medicine explained the benefits of 2,000 mg omega-3 concentrate on metabolic disease parameters synergized with the addition of chromium supplements.

“With ω-3FA, a significant, albeit modest, improvement in endothelial function, biomarkers for oxidative stress, systemic and vascular inflammation and the lipid profile was observed, but the addition of PCC, especially at a dose of 20 mg (400 µg Cr3 +), was significant increased the effectiveness of ω-3FA, ”they wrote. “All study medications were well tolerated and no serious side effects were observed. None of the subjects discontinued the study due to an adverse event that suggests the beneficial safety profile of the treatments. “

Learn more by reading Evidence-Based Natural Ways To Prevent Metabolic Disease MDlinx.

Other inflammatory diseases

In addition to metabolic syndrome, omega-3 fatty acids have been shown to reduce inflammation in a variety of other diseases. The authors of one in the published review Journal of Clinical and Translational Research stressed that omega-3 essential fatty acids such as docosahexaenoic acid (DHA), eicosapentaenoic acid (EPA), and alpha-linolenic acid (ALA) can be extracted from dietary supplements for benefits.

“EPA and DHA have been found to modulate inflammation, often by competitive inhibition of arachidonic acid use by COX and lipoxygenase enzymes, thereby producing eicosanoids that are less pro-inflammatory,” they wrote. The authors cited research suggesting that cystic fibrosis, chronic kidney disease, and asthma can benefit from omega-3 fatty acid supplementation.

Click here to learn more about foods that help with inflammation MDlinx.


Finally, COVID-19 prompted some researchers to study the effects of omega-3 supplementation on patients with the virus.

Like in the Journal of Translational Medicine, Results from a double-blind, randomized clinical trial of 128 critically ill patients with COVID-19 showed that omega-3 supplementation improved kidney and airway parameters in these patients. In particular, the experimental group showed higher 1-month survival rates and higher values ​​of arterial pH, HCO3 and base excess and lower values ​​of BUN, Cr and K compared to the control group.

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As possible mechanisms of action, the authors suggested that supplementation with DHA and EPA improves vascular reactivity and microcirculation.

Learn more about omega-3 fatty acids and other popular dietary supplements below MDlinx.


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